Crossley Lab

Manan completed a Bachelor of Science (Advanced) in 2016 and a PhD (Biochemistry and Molecular Genetics) in 2021, both at UNSW Sydney. He first joined the lab as a summer research student in 2015, and then went on to do Honours in 2016, and a PhD in 2017. Manan rejoined the lab in late 2022 as a Postdoctoral Fellow. He is investigating in vivo transcription factor binding and epigenetic mechanisms using a combination of wet and dry lab techniques. In his spare time, Manan enjoys the cricket, watching TV shows, and relaxing.

Manan’s Publications

2023

miR-365-3p mediates BCL11A and SOX6 erythroid-specific coregulation: A new player in HbF activation
miR-365-3p mediates BCL11A and SOX6 erythroid-specific coregulation: A new player in HbF activation
Michela Simbula, Maria Francesca Manchinu, Maura Mingoia, Mauro Pala, Isadora Asunis, …, Lucia Perseu, Manan Shah, Merlin Crossley, Paolo Moi, Maria Serafina Ristaldi
Molecular Therapy - Nucleic Acids  ·  01 Dec 2023  ·  doi:10.1016/j.omtn.2023.09.002
Blood and adipose-resident eosinophils are defined by distinct transcriptional profiles
Blood and adipose-resident eosinophils are defined by distinct transcriptional profiles
Manan Shah, Alexander J Knights, Emily J Vohralik, Annalise M Psaila, Kate G R Quinlan
Journal of Leukocyte Biology  ·  20 Jan 2023  ·  doi:10.1093/jleuko/qiac009

2021

<i>ACTN3</i>
            genotype influences skeletal muscle mass regulation and response to dexamethasone
ACTN3 genotype influences skeletal muscle mass regulation and response to dexamethasone
Jane T. Seto, Kelly N. Roeszler, Lyra R. Meehan, Harrison D. Wood, Chrystal Tiong, …, Manan Shah, Kate G. R. Quinlan, Paul Gregorevic, Peter J. Houweling, Kathryn N. North
Science Advances  ·  02 Jul 2021  ·  doi:10.1126/sciadv.abg0088

2020

Krüppel-like factor 3 (KLF3) suppresses NF-κB–driven inflammation in mice
Krüppel-like factor 3 (KLF3) suppresses NF-κB–driven inflammation in mice
Alexander J. Knights, Lu Yang, Manan Shah, Laura J. Norton, Gamran S. Green, Elizabeth S. Stout, Emily J. Vohralik, Merlin Crossley, Kate G.R. Quinlan
Journal of Biological Chemistry  ·  01 May 2020  ·  doi:10.1074/jbc.RA120.013114
Krüppel-like factor 3 (KLF3) suppresses NF-κB–driven inflammation in mice
Krüppel-like factor 3 (KLF3) suppresses NF-κB–driven inflammation in mice
Alexander J. Knights, Lu Yang, Manan Shah, Laura J. Norton, Gamran S. Green, Elizabeth S. Stout, Emily J. Vohralik, Merlin Crossley, Kate G.R. Quinlan
Journal of Biological Chemistry  ·  01 May 2020  ·  doi:10.1074/jbc.ra120.013114

2019

Hit and Run Transcriptional Repressors Are Difficult to Catch in the Act
Hit and Run Transcriptional Repressors Are Difficult to Catch in the Act
Manan Shah, Alister P. W. Funnell, Kate G. R. Quinlan, Merlin Crossley
BioEssays  ·  27 Jun 2019  ·  doi:/10.1002/bies.201900041
Hit and Run Transcriptional Repressors Are Difficult to Catch in the Act
Hit and Run Transcriptional Repressors Are Difficult to Catch in the Act
Manan Shah, Alister P. W. Funnell, Kate G. R. Quinlan, Merlin Crossley
BioEssays  ·  27 Jun 2019  ·  doi:10.1002/bies.201900041

2018

Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding
Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding
Gabriella E. Martyn, Beeke Wienert, Lu Yang, Manan Shah, Laura J. Norton, …, Yukio Nakamura, Richard C. M. Pearson, Alister P. W. Funnell, Kate G. R. Quinlan, Merlin Crossley
Nature Genetics  ·  01 Apr 2018  ·  doi:10.1038/s41588-018-0085-0

2016

A Quantitative Fluorescence‐Based Assay for Assessing LIM Domain–Peptide Interactions
A Quantitative Fluorescence‐Based Assay for Assessing LIM Domain–Peptide Interactions
Neil O. Robertson, Manan Shah, Jacqueline M. Matthews
Angewandte Chemie International Edition  ·  06 Oct 2016  ·  doi:10.1002/anie.201605964

Search for Dr Manan Shah's papers on the Research page